Charles Qin, MD now serving patients in Keene, NH and surrounding areas.

Benefits of Cartilage Treatment with the CARTIHEAL◊ AGILI-C◊ Cartilage Repair Implant

The CARTIHEAL AGILI-C Cartilage Repair Implant is designed to repair cartilage and bone in the knee. Patients treated with the CARTIHEAL Implant have reported significant post-operative relief of knee pain and improved knee function.1,2*

The CARTIHEAL Implant is inserted into damaged cartilage during a surgical procedure. It serves as “scaffolding” for the growth of new tissue.1,3-7 Over time, the implant is resorbed by the body, and the new tissue remains.1,3,5 

In clinical studies, the CARTIHEAL Implant has been shown to provide stronger benefits for patients than the current standard of care (microfracture and debridement). For example:

  • Better pain relief

Patients treated with the CARTIHEAL Implant reported twice the improvement of pain as patients treated with the standard of care.1,2*

  • Better clinical outcomes

The CARTIHEAL Implant has been shown to provide better clinical outcomes than the standard of care.1,2*

  • Lower risk of future surgery

Patients treated with the CARTIHEAL Implant were less likely to need a knee replacement or realignment surgery (in the following 48 months) than patients treated with the standard of care.2

Talk to your doctor to learn more about the CARTIHEAL Implant. Ask if it’s a treatment option for your knee.

All information provided on this website is for informational purposes only and is not meant as medical advice. Not everyone is a candidate for knee repair with the CARTIHEAL AGILI-C Cartilage Repair Implant, and individual results will vary. Every patient’s case is unique, and each patient should follow his or her doctor’s specific instructions. Potential risks include infection, transient or chronic pain, and swelling, among others, that may result in the need for additional medical intervention. Discuss your condition and options with your surgeon. If you are seeking this information in an emergency situation, please call 911 and seek emergency help.

◊Trademark of Smith+Nephew. 48716 12/2025

References

  1. Altschuler N, Zaslav KR, Di Matteo B, et al. Aragonite-Based Scaffold Versus Microfracture and Debridement for the Treatment of Knee Chondral and Osteochondral Lesions: Results of a Multicenter Randomized Controlled Trial. Am J Sports Med. 2023;51(4):957-967.
  2. Conte P, Anzillotti G, Crawford DC, et al. Differential analysis of the impact of lesions' location on clinical and radiological outcomes after the implantation of a novel aragonite-based scaffold to treat knee cartilage defects. Int Orthop. 2024;48(12):3117-3126.
  3. Kon E, Di Matteo B, Verdonk P, et al. Aragonite-Based Scaffold for the Treatment of Joint Surface Lesions in Mild to Moderate Osteoarthritic Knees: Results of a 2-Year Multicenter Prospective Study. Am J Sports Med. 2021;49(3):588-598.
  4. Kon E, Filardo G, Shani J, et al. Osteochondral regeneration with a novel aragonite-hyaluronate biphasic scaffold: up to 12-month follow-up study in a goat model. J Orthop Surg Res. 2015;10:81.
  5. Kon E, Robinson D, Verdonk P, et al. A novel aragonite-based scaffold for osteochondral regeneration: early experience on human implants and technical developments. Injury. 2016;47 Suppl 6:S27-S32.
  6. Chubinskaya S, Di Matteo B, Lovato L, Iacono F, Robinson D, Kon E. Agili-C implant promotes the regenerative capacity of articular cartilage defects in an ex vivo model. Knee Surg Sports Traumatol Arthrosc. 2019;27(6):1953-1964.
  7. Matta C, Szűcs-Somogyi C, Kon E, et al. Osteogenic differentiation of human bone marrow-derived mesenchymal stem cells is enhanced by an aragonite scaffold. Differentiation. 2019;107:24-34.

All information provided on this website is for information purposes only. Every patient's case is unique and each patient should follow his or her doctor's specific instructions. Please discuss nutrition, medication and treatment options with your doctor to make sure you are getting the proper care for your particular situation. If you are seeking this information in an emergency situation, please call 911 and seek emergency help.

All materials copyright © 2024 Smith & Nephew, All Rights Reserved.

Anterior Cruciate Ligament (ACL) Injury
Symptoms and treatments of ACL injury in the knee
Knee Anatomy
Learn about bones and tissues in the knee
Meniscal Tears
Symptoms and treatments of meniscal tears in the knee